Colorectal Cancer - Diagnosis and ClinicalManagement
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More About This Title Colorectal Cancer - Diagnosis and ClinicalManagement


Colorectal Cancer: Diagnosis and Clinical Management provides colorectal surgeons, gastroenterologists and oncologists with an authoritative, practical guide to best practice in the diagnosis and clinical management of colorectal cancer.

Covering all forms of treatment including surgery, chemotherapy and radiotherapy, it examines the various new and emerging therapies, new strategies for screening and prevention, as well as the latest guidance on the most challenging and controversial aspects of managing colorectal cancer.

The authors present important information on:

  • Controversies in adjuvant chemotherapy
  • Long versus short course radiotherapy
  • Minimally invasive surgery and robotics
  • Radical colonic resection

Each chapter contains key points, tips and tricks and clinical case studies to aid rapid browsing and knowledge of the basic principles, while self-assessment questions allow readers to test their clinical knowledge.

With leading international surgeons, gastroenterologists and oncologists combining to offer their considerable wealth of expertise and knowledge, Colorectal Cancer is a well-balanced, indispensable resource for all those involved in colorectal cancer management. 



John H. Scholefield, FRCS, ChM, Head, Division of GI Surgery & Professor of Surgery, University Hospital, Nottingham, UK

Cathy Eng, MD, FACP, Associate Professor & Associate Medical Director, Colorectal Center, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA


Contributors, vii

Part 1 Diagnosis

1 Epidemiology, 3
Mala Pande & Marsha L. Frazier

2 Screening for colorectal cancer, 27
Robert JC Steele & Paula MacDonald

3 Management of adenomas, 51
Sunil Dolwani, Rajvinder Singh, Noriya Uedo & Krish Ragunath

Part 2 Histopathology

4 How histopathology affects the management of the multidisciplinary team, 69
Dipen Maru

Part 3 Surgical

5 Radical colonic resection, 87
Kenichi Sugihara, Yusuke Kinugasa & Shunsuke Tsukamoto

6 ExtraLevator AbdominoPerineal Excision (ELAPE) for advanced low rectal cancer, 104
Brendan J. Moran & Timothy J. Moore

7 Neoadjuvant therapy without surgery for early stage rectal cancer?, 126
Thomas D. Pinkney & Simon P. Bach

8 Minimally invasive surgery for rectal cancer and robotics, 150
David Jayne & Gregory Taylor

9 Surgery for anal cancer, 163
John H. Scholefield

Part 4 Oncology

10 Controversies in adjuvant chemotherapy, 179
Stephen Staal, Karen Daily & Carmen Allegra

11 Long- versus short-course radiotherapy for rectal cancer, 200
Manisha Palta, Christopher G. Willett & Brian G. Czito

12 More treatment is not necessarily better – limited options for chemotherapeutic radiosensitization, 218
Daedong Kim

13 Controversies in advanced disease – surgical approaches for metastatic resection, 227
Amanda B. Cooper, Thomas A. Aloia, Jean-Nicolas Vauthey & Steven A. Curley

14 Controversies in chemotherapy in advanced colorectal cancer, 243
Ludmila Katherine Martin & Tanios Bekaii-Saab

Part 5 Outcomes

15 What is the role of surveillance for colorectal cancer?, 263
Daedong Kim

Part 6 Vignettes

16 The young patient with colorectal cancer – genetic counseling discussion, 275
Sarah Bannon, Maureen E. Mork & Miguel A. Rodriguez-Bigas

17 Best practices of supportive care while receiving chemotherapy, 286
Maura Polansky

18 Palliative care vignettes, 292
Jenny Wei & Egidio Del Fabbro

Index, 299