Urgent Interventional Therapies
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More About This Title Urgent Interventional Therapies


Illustrating the differences between urgent interventions and interventions performed to manage chronic conditions the authors present the chapters in a consistent template for ease of use covering; background, indications, evidence review, device description, procedural techniques, follow-up care, and complications.

  • Shows the differences between interventions performed to manage chronic conditions and interventions that are truly urgent
  • Chapters follow a consistent structure from background through indications, evidence review, device description, procedural techniques to follow-up care and complications
  • More than 40 high definition videos, hosted on  companion website www.wiley.com/go/kipshidze/interventionaltherapies, complete with tips and tricks, provide a visual learning tool


Nicholas Kipshidze, MD, PhD, DSc, FACC, FESC, FSCAI, Professor of Medicine and Surgery, Director of Endovascular Therapies, New York Cardiovascular Research, New York, NY, USA; Consultant Cardiologist, N. Kipshidze Central University Hospital, Tbilisi, Georgia. 

Jawed Fareed, PhD, FACB, Professor of Pathology and Pharmacology, Director of Hemostasis and Thrombosis Research Laboratories and Department of Pathology, Loyola University, Stritch School of Medicine, Maywood, IL, USA

Robert J. Rosen, MD, Director, Interventional Radiology and Endovascular Surgery, Lenox Hill Heart and Vascular Institute, New York, NY, USA

George Dangas, MD, PhD, FACC, FAHA, FESC, FSCAI, Professor of Cardiology and Vascular Surgery, Director, Cardiovascular Innovation, Mount Sinai Medical Center, New York, NY, USA

Patrick W. Serruys, MD, PhD, FESC, FACC, Emeritus Professor of Medicine, Chair in Interventional Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands; Professor of Cardiology, Imperial College, London, UK


List of Contributors, viii

Foreword, xv

Preface, xvii

Abbreviations, xviii

About the Companion Website, xxii

Part 1 Cardiac Interventions

Section I Acute Coronary Syndrome

1 Acute Coronary Syndrome: Guidelines and Definitions, 3
Elias A. Sanidas, Roxana Mehran & George Dangas

2 Cardiac Biomarkers in Acute Cardiac Care, 9
Jonathan D. Marmur, Sanjay Kumar & Antony L. Innasimuthu

3 Diagnosis of Vulnerable Plaque, 19
Konstantinos Toutouzas, Antonios Karanasos & Christodoulos Stefanadis

4 Management of Thrombotic Disorders: Heparin to Newer Anticoagulants, 27
Jawed Fareed, Evi Kalodiki & Debra Hoppensteadt

5 Newer Antiplatelet Agents for Interventional Indications, 41
Wiktor Kuliczkowski & Victor Serebruany

6 Genetic Considerations of Antiplatelet Therapy, 49
Fabiana Rollini, Antonio Tello-Montoliu & Dominick J. Angiolillo

7 Anticoagulant Management of Heparin-Compromised Patients, 60
Jeanine M. Walenga & Mamdouh Bakhos

8 Management of Bleeding in Urgent Interventions, 66
Rakesh Wahi & Debra Hoppensteadt

9 Role of Newer Anti-Xa and Anti-IIa Agents for Interventions, 77
Brigitte Kaiser

10 Treatment of NSTEMI Patients, 86
Kirk N. Garratt & Jonathon Habersberger

11 Treatment of Patients with STEMI, 91
Carsten Stengaard, Jacob Thorsted Sørensen, Christian Juhl Terkelsen & Michael Maeng

12 Mechanical Removal of Thrombus from Culprit Lesions: Current Devices and Future Developments, 99
Zoran Lasic

13 Role of Intravenous Fibrinolytic Therapy, 105
Freek W.A. Verheugt

14 The Transradial Approach in Patients with Acute Coronary Syndromes, 110
Jeffrey M. Schussler

15 Intervention for Failed Grafts, 117
Michael S. Lee & Gopi Manthripragada

16 Excimer Laser for Revascularization in AMI, 126
On Topaz, Allyne Topaz & Kristine Owen

17 Management of Patients Presenting too Late for PTCA, 137
Giampaolo Niccoli, Cristina Aurigemma & Filippo Crea

18 Is There a Role for Drug-Eluting Balloons in Treatment of Acute Coronary Syndromes?, 146
Anouar Belkacemi, Pierfrancesco Agostoni, Michiel Voskuil, Kevin Onsea, Pieter Doevendans & Pieter Stella

19 Cardiogenic Shock: Outcomes, Treatment, and Role of Hemodynamic Support, 152
Eugenia Nikolsky, Amit Soni & Rafael Beyar

20 Management of Patients after Acute Coronary Syndrome, 171
Davide Capodanno & George Dangas

21 Emergency PTCA or CABG for Left Main Disease?, 179
Gill Louise Buchanan, Alaide Chieffo & Antonio Colombo

Section II Urgent Electrophysiology

22 Management of Reperfusion Arrhythmias, 187
Zviad Matoshvili & Nicholas Kipshidze

23 Ablative Therapies in Arrhythmia Emergencies, 192
Francesco Santoni-Rugiu

Section III Other Acute Cardiac Conditions

24 Principles of Interventions in Acute Structural Heart Disease, 198
Jennifer Franke, Stefan C. Bertog, Ilona Hofmann & Horst Sievert

25 Acute Interventional Therapies for Pulmonary Embolism, 201
Ian del Conde & Barry T. Katzen

26 Transcatheter Aortic Valve Implantation, 209
Thomas M. Snow, Neil Moat, Simon Davies, Sarah Barker, Alison Duncan & Carlo di Mario

27 Acute Mitral Interventions, 221
José A. Condado, Carlos Calderas & José F. Condado

28 Mitral and Aortic Valve Balloon Valvotomy, 231
Sumith Aleti, Jawahar L. Mehta & Rajesh Sachdeva

29 Postinfarction Ventricular Septal Defect, 238
Holger Thiele, Steffen Desch, Gerhard Schuler & Suzanne de Waha

30 Transcatheter VSD Closure, 244
Damien Kenny, Qi-Ling Cao & Ziyad M. Hijazi

31 Atrial Septostomies, 253
Carlos A.C. Pedra

32 Transcatheter Pulmonary Valve Replacement, 265
Noa Holoshitz, Qi-Ling Cao & Ziyad M. Hijazi

Part 2 Peripheral Interventions

Section IV Cerebrovascular Disorders 33 How to Set Up an Acute Stroke Service, 279
Iris Q. Grunwald, Peter Marlow, Stefan C. Bertog & Anna Luisa Kühn

34 Acute Stroke Intervention, 286
Stefan C. Bertog, Iris Q. Grunwald, Anna Luisa Kühn, Jennifer Franke, Ilona Hofmann & Horst Sievert

35 New Devices for Exclusion of Cerebral Aneurysms, 302
Gyula Gál

Section V Treatment of Critical Leg Ischemia

36 Principles of Diagnosis for, and Interventional Treatment of, Critical Leg Ischemia, 313
Gary D. Kiernan, Hatim Yagoub, Brian G. Hynes, Thomas J. Kiernan & Michael R. Jaff

37 Iliac and SFA Interventions in Patients with Critical Limb Ischemia, 321
Farah G. Irani, Apoorva Gogna, Benjamin S.Y. Chua & Manish Taneja

38 Role of Atherectomy in Below-the-Knee Vessels in Critical Limb Ischemia, 331
Jihad A. Mustapha, Larry J. Diaz-Sandoval & Fadi A. Saab

39 Interventions in Below-the-Knee Lesions in Critical Limb Ischemia, 338
Jose Wiley, Prakash Krishnan & Arthur Tarricone

40 Management of Diabetic Foot following Percutaneous Transluminal Angioplasty, 348
Laura Kerselaers, Jürgen Verbist, Koen Keirse, Koen Deloose, Marc Bosiers & Patrick Peeters

Section VI Treatment of Acute Aortic Disorders

41 Thoracic Aortic Dissections: Perspectives for Endovascular Management, 353
Grayson H. Wheatley III

42 Management of Acute Aortic Syndrome, 358
Ibrahim Akin, Stephan Kische, Tim C. Rehders, Hüseyin Ince & Christoph A. Nienaber

43 Urgent Endovascular Renal Intervention, 366
On Topaz & Massoud A. Leesar

44 Catheter Interventions in Acute Ischemia of the Upper Extremities, 376
Glenn W. Stambo

Part 3 Urgent Radiology

45 Transjugular Intrahepatic Portosystemic Shunt, 391
Juan Carlos Garcia-Pagán, Juan G. Abraldes & Jaume Bosch

46 Chemoembolization of Hepatic Malignancies, 403
Nikhil Bhagat & Jean-Francois Geschwind

47 Pulmonary Arteriovenous Malformations, 410
Robert J. Rosen & Naiem Nassiri

48 Interventional Management of Vascular Malformations, 419
Robert J. Rosen & Jennifer Drury

49 Interventions for Mesenteric Ischemia, 442
Robert J. Rosen & Amit Jain

50 Acute Gastrointestinal Arterial Bleeding, 458
Romaric Loffroy

51 Vena Cava Filters, 467
Parveen Warner & Raman Uberoi

52 Uterine Fibroid Embolization, 474
Mark A. Westcott

Part 4 Innovative Therapies

53 New Stents for Acute Coronary Syndrome, 485
Mony Shuvy & Chaim Lotan

54 Cell Therapy for Acute Myocardial Infarction, 497
Bodo-Eckehard Strauer & Gustav Steinhoff

55 Aqueous Oxygen for Treatment of ST-Segment Elevation Myocardial Infarction, 502
Neelima Katukuri, Jeffrey L. Creech & James Richard Spears

56 Endovascular Hypothermia in Acute Myocardial Infarctions, 509
David Erlinge

57 Angiogenesis in the Treatment of Critical Limb Ischemia, 514
Jason A. Chin, Zankhana Raval, Melina R. Kibbe & Douglas W. Losordo

58 Catheter-Directed Ultrasound-Accelerated hrombolysis for the Treatment of Acute Pulmonary Embolism, 534
Tod C. Engelhardt

59 Transcoronary and Left Ventricular Temporary Pacing, 541
Crochan J. O’Sullivan & Bernhard Meier

60 Extracorporeal Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds, 549
Rainer Mittermayr & Wolfgang Schaden

Index, 559


“Any cardio interventionist or radiologist interested in the processes and applications of urgent interventions will find this packed with technical expert advice on all stages of treatment.”  (Midwest Book Review, 1 August 2015