Basics of Blood Management 2e
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To reduce transfusion-related morbidity and mortality, it is recommended that an integrated approach to blood management is employed using all available tools to reduce a patient's exposure to donor blood. Meeting the need for a book covering the concepts of blood management as a trend towards multidisciplinary blood management, this new edition is an important resource, providing healthcare professionals with a tool to develop background knowledge in blood management, its organization, methods and tools. Practicing clinicians will be fully prepared to successfully start and run blood management programs.


Dr Petra Seeber, Department of Anesthesiology, Critical Care, Pain Management and Emergency Medicine, HELIOS Klinik, Blankenhain, Germany.

Aryeh Shander, MD, is Clinical Professor of Anesthesiology, Medicine and Surgery at the Mount Sinai School of Medicine in New York City, Chief, Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ.
Dr Shander lectures nationally and internationally on a variety of topics relating to blood conservation, volume resuscitation, acute anemia therapy, surgical blood management, acute normovolemic hemodilution and bloodless medicine and surgery. His publications have appeared in The Lancet, the journal Transfusion, and Transfusion Alternatives in Transfusion Medicine, for which he serves in Editorial and Scientific Boards.
He serves as Chief Executive Officer of the Society for the Advancement of Blood Management and is Fellow of the American College of Critical Care Medicine and the American College of Chest Physicians. Dr Schander is a member of the American Society of Critical Care Anesthesiologists where he serves on committees, both locally and nationally, and in addition, is a member of the American Association of Blood Banks (AABB), American Society of Anesthesiologists (ASA) and a founding member of the American Society of Critical Care Anesthesiologists (ASCCA). In 1997 Dr Shander was recommended by Time magazine as one of America's "Heroes of Medicine".


Preface, vii

Preface to the First Edition, viii

1 History and Organization of Blood Management, 1

2 Physiology of Anemia and Oxygen Transport, 9

3 Anemia Therapy I: Erythropoiesis-Stimulating Agents, 21

4 Anemia Therapy II: Hematinics, 36

5 Growth Factors, 51

6 Fluid Management, 67

7 Chemistry of Hemostasis, 81

8 Recombinant Blood Products, 100

9 Artificial Blood, 109

10 Oxygen Therapy, 124

11 Preparation of the Patient for Surgery, 139

12 Iatrogenic Blood Loss, 160

13 Physical Methods of Hemostasis, 173

14 Anesthesia—More than Sleeping, 191

15 Use of Autologous Blood, 201

16 Cell Salvage, 212

17 Blood-Derived Pharmaceuticals, 229

18 Transfusion Medicine, 245

19 Step by Step to an Organized Blood Management Program, 262

20 Law, Ethics, Religion, and Blood Management, 285

Appendix A: Detailed Information, 297

Appendix B: Sources of Information for Blood Management, 305

Appendix C: Program Tools and Forms, 309

Appendix D: Teaching Aids: Research and Projects, 323

Index, 327


“This is a valuable guide if you are interested in setting up a blood management program for your organization.”  (Doody’s, 15 February 2013)