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- Wiley
More About This Title Personalizing Precision Medicine: A Global Voyagefrom Vision to Reality
English
• Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide
• Reviews precision medicine around the world, including the US, China, Japan, the Middle East, India, Europe, and Latin America
• Discusses a number of diseases areas – cancer, cardiovascular, neurodegenerative, infectious disease, pain, immunology, rare diseases
• Includes information and quotes from over 100 interviews with key industry experts in biotech, pharma, informatics, diagnostics, health providers, advocacy groups, and more.
• Includes stories illustrating current issues and future promises in precision medicine for a human touch
English
Kristin Ciriello Pothier is the Global Head of Life Sciences for the Parthenon-EY practice of Ernst & Young LLP. She has over 20 years of experience in management consulting and research in the life sciences industry. She is a noted speaker, workshop leader, and writer in life sciences. She is also a clinical laboratory and life sciences innovation expert, helping develop product and service strategies worldwide for investors, corporations, and medical institutions. She earned an undergraduate degree in Biochemistry from Smith College and a graduate degree in Epidemiology, Health Management, and Maternal and Child Health from the Harvard School of Public Health. She lives in Massachusetts with her husband and their two lively children.
English
Acknowledgments vii
Introduction ix
Methodology xiii
About the Author xv
Part 1 The History 1
1 The Right Drug, the Right Patient, the Right Time: Foundations of Precision Medicine 3
2 Decision?-Making Machines: Diagnostics in Precision Medicine 27
3 Precision Medicine around the World: Europe 37
Part 2 The Present 51
4 Our Reality Today: The Patient Journey in Precision Medicine 53
5 Toward the Day We Just Call It “Medicine”: Access to Precision Medicine 65
6 Precision Medicine around the World: Japan 81
7 Shifting Rules: Regulation and Reimbursement in Precision Medicine 89
8 Precision Medicine around the World: Latin America 105
9 Patients as the Poorest Princesses: Supportive Care in Precision Medicine 125
10 Informatics under the Hood: Information in Precision Medicine 135
11 Precision Medicine around the World: India 149
Part 3 The Future 157
12 A Personalized Stomach: Precision Medicine beyond Cancer 159
13 Consumer Is King: Consumer Applications of Precision Medicine 181
14 Precision Medicine around the World: The Middle East 197
15 Sci?-Fi Potential: CRISPR as the Next Novel Frontier in Precision Medicine 207
16 Precision Medicine around the World: China 223
17 A New Hope: The Future of Precision Medicine 231
Afterword 241
Index 243
English
“A tour de force - Kristin brings Precision Medicine into focus with clear and practical commentary. Personalizing Precision Medicine is exactly what healthcare establishment needs now - how to make it real and cost effective.” – Mara Aspinall, President and CEO, Health Catalysts, Co-Founder, Arizona State University School of Biomedical Diagnostics
“As a surgeon, I find the importance of precision surgery to be obvious, but describing precision medicine has been a challenge – until now! Kristin explains it all, from the basic science to compelling, personal stories that make the science come to life. It helps us examine precision medicine from all angles and helps us as physicians explain it comprehensively to others.” – Tenley Albright, Director of the MIT Collaborative Initiatives, former surgeon, and World and Olympic Champion figure skater
“As a young patient with breast cancer, it was overwhelming to research every aspect of my care to make sure it was personalized for me. This book, Personalizing Precision Medicine, should be one of the very first tools to educate people like me, and those professionals who supported me. The facts, mixed with personal stories from all around the world, were something I wish I’d had when I was first diagnosed.” – Liz Lord, Breast cancer slayer, former US diplomat and owner of ArlVa Homes LLC
