What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice
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More About This Title What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice

English

Designer Mice: Scope and Sourcebooks.

Of Unicorns and Chimeras: How to Generate a Transgenic or Knockout Mouse

General Health: Give Your Mouse a Physical;
Neurological Reflexes.

Motor Functions: Open Field, Holeboard, Rotarod, Balance, Grip, Circadian Activity, Circling, Stereotypy, Ataxic Gait, Seizures.

Sensory Abilities: Olfaction, Vision, Hearing, Taste, Touch, Nociception.

Learning and Memory: Morris Swim Task, Spatial Mazes, Cued and Contextual Conditioning, Conditioned Taste Aversion, Conditioned Eye Blink, Olfactory Discrimination, Social Recognition, Passive Avoidance, Schedule Controlled Operant Tasks, Motor Learning.

Feeding and Drinking: Daily Consumption, Restricted Access, Choice Tests, Microstructural Analysis.

Reproductive Behaviors: Sexual and Parental Behaviors.

Social Behaviors: Social Interaction, Nesting, Grooming, Juvenile Play, Aggression.

Emotional Behaviors: Animal Models of Psychiatric Disorders: Fear, Anxiety, Depression, Schizophrenia.

Reward: Self-Administration of Additive Drugs, Conditioned Place Preference.

The Next Generation: Conditional and Inducible Mutations, Quantitative Trait Loci Analysis, Chemical Mutagenesis, Gene Therapy, Ethical Issues.

Bibliography.

index.

English

"Very timely and will enable the non-behavioral scientist to make informed decisions on what behavioral tests are needed and with whom they should collaborate."--Nature Neuroscience

"Overall an excellent book. The book succesfully brings together the field of behavioral neuroscience and the rewards and insights that can be gained using this approach. I would reccomend that every behavioral scientist has at least two copies, one for their own use and one that will be on permanent loan to their students, post-doctoral students,and colleagues in molecular biology."--TRENDS in Pharmacological Sciences"This is an excellent and timely book. I have been looking for an appropriate textbook for graduate students who are interested in using genetically engineered mice in various behavioral paradigms, and this is definitely the one to recommend." --Noboru Hiroi, Ph.D., Albert Einstein College of Medicine
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