Approaches to Gene Mapping in Complex Human Diseases
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More About This Title Approaches to Gene Mapping in Complex Human Diseases
English
Overview of Mapping Common and Genetically Complex Human Disease Traits (J. Haines & M. Pericak-Vance).
Basic Concepts in Genetics (M. Speer).
Defining Disease Phenotypes (A. Aylsworth).
Basic Concepts in Linking Analysis (M. Pericak-Vance).
Determining the Genetic Component of a Disease (L. Farrer & L. Cupples).
Patient and Family Participation in Genetic Research Studies (P. Cohen & C. Wolpert).
Sample Size and Power (M. Speer).
The Collection of Biological Samples for DNA Analysis (J. Vance).
Methods of Geneotyping (J. Vance & K. Othmane).
Database Design for Gene Mapping Studies (C. Haynes & C. Blach).
Genomic Screening (J. Haines).
Lod Score Analysis (J. Xu, et al.).
Sib Pair Analysis (D. Goldgar).
Affected Relative Pair Analysis (J. Haines).
Linkage Disequilibrium and Allelic Association (M. Pericak-Vance).
Using Public Databases (J. Haines).
Laboratory Approaches Toward Gene Identification (D. Marchuk).
Examining Complex Genetic Interactions (J. Schildkraut).
Glossary.
Appendix.
Index.
Basic Concepts in Genetics (M. Speer).
Defining Disease Phenotypes (A. Aylsworth).
Basic Concepts in Linking Analysis (M. Pericak-Vance).
Determining the Genetic Component of a Disease (L. Farrer & L. Cupples).
Patient and Family Participation in Genetic Research Studies (P. Cohen & C. Wolpert).
Sample Size and Power (M. Speer).
The Collection of Biological Samples for DNA Analysis (J. Vance).
Methods of Geneotyping (J. Vance & K. Othmane).
Database Design for Gene Mapping Studies (C. Haynes & C. Blach).
Genomic Screening (J. Haines).
Lod Score Analysis (J. Xu, et al.).
Sib Pair Analysis (D. Goldgar).
Affected Relative Pair Analysis (J. Haines).
Linkage Disequilibrium and Allelic Association (M. Pericak-Vance).
Using Public Databases (J. Haines).
Laboratory Approaches Toward Gene Identification (D. Marchuk).
Examining Complex Genetic Interactions (J. Schildkraut).
Glossary.
Appendix.
Index.
English
"The book provides a useful compendium of information for those who wish to embark on gene mapping studies. The editors are to be commended on taking on such a difficult task." --Analytical Biochemistry, Volume 270, 1999
