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Genetics and Cancer Susceptibility: Implications for Risk Assessment PCBR - V# unknown
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More About This Title Genetics and Cancer Susceptibility: Implications for Risk Assessment PCBR - V# unknown

  • English

English

Specialists in their respective fields review the impact of both intrinsic genetic factors and extrinsic modifiers on human cancer risk. The book's main thrust is on susceptibility factors that are targets for chemical carcinogens, intrinsic factors that modify cancer risk and biomonitoring and extrinsic risk modification.
  • English

English

Partial table of contents:

The Role of p53 Loss in Genomic Instability and Tumor Progression in a Murine Mammary Cancer Model (L. Donehower, et al.).

Genetic Susceptibility to In Vivo and In Vitro Chemical Transformation (C. Walker).

Genetic Analysis of Multistage Hepatocarcinogenesis (T. Poole, et al.).

Genetic Susceptibility to Tumor Progression in Mouse Skin Carcinogenesis (M. Stern & C. Conti).

One Decade of Comparative Molecular Carcinogenesis (T. Goodrow).

Validation Issues for the Use of Transgenic Mouse Mutation Assays in Risk Assessment (N. Gorelick).

Molecular Epidemiology (P. Shields).

Epidemiology of Susceptibility to Breast Cancer (B. Hulka).

From Host Factors to Genetic Susceptibility (P. Kleihues & B. Stewart).

Diet Intervention in Modifying Cancer Risk (D. Birt, et al.).

Index.

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