Surface Enhanced Raman Spectroscopy - Analytical,Biophysical and Life Science Applications
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More About This Title Surface Enhanced Raman Spectroscopy - Analytical,Biophysical and Life Science Applications
English
Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical
and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems.
From the contents:
* Theory and practice of SERS
* Analytical applications
* SERS combined with other analytical techniques
* Biophysical applications
* Life science applications including various microscopies
Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.
and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems.
From the contents:
* Theory and practice of SERS
* Analytical applications
* SERS combined with other analytical techniques
* Biophysical applications
* Life science applications including various microscopies
Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.
English
Sebastian Schlücker obtained his undergraduate and PhD degrees at the University of Würzburg, Germany. After a postdoctoral stay at the US National Institutes of Health (NIH), Bethesda, Maryland, USA from 2002 till 2004, he completed his Habilitation in Physical Chemistry at the University of Würzburg in 2006. He has been Professor of Experimental Physics at the University of Osnabrück, Germany since 2008.
English
Preface
BASIC ELECTROMAGNETIC THEORY OF SERS
Introduction
Plasmon Resonances and Field Enhancements
Field Enhancement Distribution and Localization
Electromagnetic Model for the SERS and Fluorescence Enhancement Factors
The Magnitude of the SERS Enhancement Factor in Typical Cases
Conclusions
NANOPARTICLE SERS SUBSTRATES
Introduction
Preparation and Stability of Metal Nanoparticle Colloidal SERS Substrates
Characterization of Nanoparticle-Based SERS Substrates
Nanoparticles on the Unfunctionalized Solid Surface as SERS Substrates
Conclusion and Outlook
QUANTITATIVE SERS METHODS
Introduction
SERS Media
Stability and Shelf Life
Reproducibility and Internal Standards
Selectivity
Conclusion
SINGLE-MOLECULE- AND TRACE DETECTION BY SERS
Introduction
Experiments and Results
Conclusions
DETECTION OF PERSISTENT ORGANIC POLLUTANTS BY USING SERS SENSORS BASED ON ORGANICALLY FUNCTIONALIZED Ag NANOPARTICLES
Introduction
Inclusion Hosts
Contact Hosts
Occlusion Hosts
Conclusions
SERS AND PHARMACEUTICALS
Introduction
SERS of Antipyretics and Analgesics
SERS of Antimalarials
SERS of Anticarcinogenics andf Antimutagenics
Concluding Remarks
SERS AND SEPARATION SCIENCE
Introduction
SERS and Capillary Electrophoresis (CE)
SERS and Liquid Chromatography (LC)
SERS and Gas Chromatography (GC)
SERS and Thin Layer Chromatography (TLC)
Other Separation Methods
Conclusions
SERS AND MICROFLUIDICS
Introduction
Lab-on-a-Chip Technology
Microfluidic Platforms and Application for SERS
Summary
ELECTROCHEMICAL SERS AND ITS APPLICATION IN ANALYTICAL, BIOPHYSICAL AND LIFE SCIENCE
Electrochemical Surface-Enhanced Raman Spectroscopy
Features of Electrochemical Surface-Enhanced Raman Spectroscopy
Experimental Techniques of EC-SERS
Applications of EC-SERS
Perspectives
ELECTRON TRANSFER OF PROTEINS AT MEMBRANE MODELS
Introduction
Model Membranes and Membrane Models
Methods for Probing Electron Transfer Processes of Cytochrome c at Coated Electrodes
The Unusual Distance Dependence of the Interfacial Electron Transfer Process
Electron Transfer and Protein Orientational Dynamics
Electric Field Effects on the Electron Transfer Dynamics
Electron Transfer and Protein Structural Changes
Overall Description of the Mechanism and Dynamics of the Interfacial Processes
Interfacial Electric Fields and the Biological Functions of Cytochrome c
QUANTITATIVE DNA ANALYSIS USING SURFACE-ENHANCED RESONANCE RAMAN SCATTERING
Introduction
SERRS Surfaces
Raman Reporters
SERRS DNA Probes
Sensitivity
Multiplexing
Assays
Conclusion
SERS MICROSCOPY: NANOPARTICLE PROBES AND BIOMEDICAL APPLICATIONS
Introduction
SERS Nanoparticle Probes
Biomedical Applications of SERS Microscopy
Summary and Outlook
1-P AND 2-P EXCITED SERS AS INTRACELLULAR PROBE
From Tags to Probes: Challenges in Intracellular Probing
Probing of Intracellular Parameters
Surface-Enhanced Hyper Raman Scattering and Its Potential in Studies of Cells
SURFACE- AND TIP-ENHANCEMENT CARS
Introduction
CARS: Coherent Anti-Stokes Raman Scattering
Local Enhancement of CARS by Metallic Nanostructures
Surface-Enhanced CARS
Tip-Enhanced CARS
BASIC ELECTROMAGNETIC THEORY OF SERS
Introduction
Plasmon Resonances and Field Enhancements
Field Enhancement Distribution and Localization
Electromagnetic Model for the SERS and Fluorescence Enhancement Factors
The Magnitude of the SERS Enhancement Factor in Typical Cases
Conclusions
NANOPARTICLE SERS SUBSTRATES
Introduction
Preparation and Stability of Metal Nanoparticle Colloidal SERS Substrates
Characterization of Nanoparticle-Based SERS Substrates
Nanoparticles on the Unfunctionalized Solid Surface as SERS Substrates
Conclusion and Outlook
QUANTITATIVE SERS METHODS
Introduction
SERS Media
Stability and Shelf Life
Reproducibility and Internal Standards
Selectivity
Conclusion
SINGLE-MOLECULE- AND TRACE DETECTION BY SERS
Introduction
Experiments and Results
Conclusions
DETECTION OF PERSISTENT ORGANIC POLLUTANTS BY USING SERS SENSORS BASED ON ORGANICALLY FUNCTIONALIZED Ag NANOPARTICLES
Introduction
Inclusion Hosts
Contact Hosts
Occlusion Hosts
Conclusions
SERS AND PHARMACEUTICALS
Introduction
SERS of Antipyretics and Analgesics
SERS of Antimalarials
SERS of Anticarcinogenics andf Antimutagenics
Concluding Remarks
SERS AND SEPARATION SCIENCE
Introduction
SERS and Capillary Electrophoresis (CE)
SERS and Liquid Chromatography (LC)
SERS and Gas Chromatography (GC)
SERS and Thin Layer Chromatography (TLC)
Other Separation Methods
Conclusions
SERS AND MICROFLUIDICS
Introduction
Lab-on-a-Chip Technology
Microfluidic Platforms and Application for SERS
Summary
ELECTROCHEMICAL SERS AND ITS APPLICATION IN ANALYTICAL, BIOPHYSICAL AND LIFE SCIENCE
Electrochemical Surface-Enhanced Raman Spectroscopy
Features of Electrochemical Surface-Enhanced Raman Spectroscopy
Experimental Techniques of EC-SERS
Applications of EC-SERS
Perspectives
ELECTRON TRANSFER OF PROTEINS AT MEMBRANE MODELS
Introduction
Model Membranes and Membrane Models
Methods for Probing Electron Transfer Processes of Cytochrome c at Coated Electrodes
The Unusual Distance Dependence of the Interfacial Electron Transfer Process
Electron Transfer and Protein Orientational Dynamics
Electric Field Effects on the Electron Transfer Dynamics
Electron Transfer and Protein Structural Changes
Overall Description of the Mechanism and Dynamics of the Interfacial Processes
Interfacial Electric Fields and the Biological Functions of Cytochrome c
QUANTITATIVE DNA ANALYSIS USING SURFACE-ENHANCED RESONANCE RAMAN SCATTERING
Introduction
SERRS Surfaces
Raman Reporters
SERRS DNA Probes
Sensitivity
Multiplexing
Assays
Conclusion
SERS MICROSCOPY: NANOPARTICLE PROBES AND BIOMEDICAL APPLICATIONS
Introduction
SERS Nanoparticle Probes
Biomedical Applications of SERS Microscopy
Summary and Outlook
1-P AND 2-P EXCITED SERS AS INTRACELLULAR PROBE
From Tags to Probes: Challenges in Intracellular Probing
Probing of Intracellular Parameters
Surface-Enhanced Hyper Raman Scattering and Its Potential in Studies of Cells
SURFACE- AND TIP-ENHANCEMENT CARS
Introduction
CARS: Coherent Anti-Stokes Raman Scattering
Local Enhancement of CARS by Metallic Nanostructures
Surface-Enhanced CARS
Tip-Enhanced CARS
English
“The book Surface Enhanced Raman Spectroscopy: Analytical, Biophysical and Life Science Applications provides a well-balanced account of the basic principles of SERS, advances in the SERS method, and applications of SERS technology. The book is expected to become a valuable resource for researchers in the field of SERS and those from other fields who are interested in exploiting SERS technology in a growing number of analytical, biophysical and life science applications.” (Anal Bioanal Chem, 2011)
"I highly recommend it to any researcher in materials science and spectroscopy as well as any researchers in surface and medicinal chemistry and biophysics with some background in molecular spectroscopy. The 14 chapters masterfully guide the reader through a fascinating field in which researchers have been very active over the last decade." (Optics & Photonics News, 5 August 2011)
